The opinion of 10,000 men is of no value if none of them knows anything about the subject.
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Gender-neutral version:
The opinion of 10,000 people is of no value if none of them knows anything about the subject.
The opinion of 10,000 men is of no value if none of them knows anything about the subject.
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Gender-neutral version:
The opinion of 10,000 people is of no value if none of them knows anything about the subject.